Spinphox
WebJan 23, 2012 · Catalytic asymmetric synthesis of aromatic spiroketals by spinphox/iridium(I)-catalyzed hydrogenation and spiroketalization of α,α'-bis(2-hydroxyarylidene) ketones. January 23, 2012 WebJan 23, 2012 · From spiro to spiro: An iridium(I) complex with a spiral P,N ligand (SpinPhox) is highly efficient in the catalytic asymmetric hydrogenation of α,α′‐bis(2‐hydroxyarylidene) ketones to afford the corresponding aromatic spiroketals in high yields with excellent diastereo‐ and enantioselectivities (see scheme). The complex plays a dual role in the …
Spinphox
Did you know?
WebOct 1, 2024 · The first asymmetric hydrogenation of 3-ylidenephthalides has been developed using the Ir I complex of a spiro[4,4]-1,6-nonadiene-based phosphine-oxazoline ligand … WebTake it for a spin: SpinPhox/Ir I complexes are highly efficient and versatile in the enantioselective hydrogenation of a broad spectrum of exocyclic α,β-unsaturated …
WebThe utility of SpinPHOX ligand was exemplified by the reduction of α,α-bisbenzylidene derivatives to furnish spiro-acetal compounds in high enantioselectivity (Scheme 11). Substituents on the phenol ring did not influence the reaction. Iridium (III) species generated by the reduction of the iridium complex played a role as a WebOct 10, 2014 · Herein, SpinPhox/IrI catalysts have been demonstrated to be highly enantioselective in the asymmetric hydrogenation of the C C bonds in the exocyclic …
WebAlfa Chemistry offers 1,5-cyclooctadiene{(4S)-(-)-2-[(5R)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-phenyloxazole}iridium(I) tetrakis[3,5-bis ... WebApr 19, 2012 · An Ir/SpinPHOX complex catalyzed double asymmetric hydrogenation of 3,6-dialkylidene-1,4-dimethylpiperazine-2,5-dione has been developed, providing an efficient and practical access to a wide ...
WebJul 2, 2014 · Wang X, Han Z, Wang Z, Ding K. Catalytic asymmetric synthesis of aromatic spiroketals by spinphox/iridium(I)-catalyzed hydrogenation and spiroketalization of α,α′ …
Web张翱，男，博士、中国科学院上海药物所研究员、博士生导师、国家杰出青年基金获得者、中国科学院“百人计划”择优支持和上海“浦江人才计划”优秀奖获得者。现为上海科技大学生命科学与技术学院特聘教授。主要从事化学生物学及药物化学研究，尤其是针对神经精神性与肿瘤两大疑难疾病 ... hunter x hunter 3d lampWebOptically active medium-sized cyclic carbonyl compounds bearing an α-chiral carbon center are of interest in pharmaceutical sciences and asymmetric synthesis. Herein, … hunter x hunter 2022 calendarWebDec 14, 2011 · From spiro to spiro: An iridium(I) complex with a spiral P,N ligand (SpinPhox) is highly efficient in the catalytic asymmetric hydrogenation of α,α′-bis(2-hydroxyarylidene) … hunter x hunter anime japan 2022WebJun 5, 2024 · An Ir/spiro[4,4]-1,6-nonadiene-based phosphine-oxazoline ligand (SpinPHOX) complex-catalyzed double asymmetric hydrogenation of 3,6-dialkylidene-1,4 … hunter x hunter alalay ni kurapikachicken tikka اماكنWebSep 9, 2010 · A new type of chiral bisoxazoline ligands 1 based on spiro[4,4]-1,6-nonadiene backbone was easily prepared in six steps from racemic spiro[4,4]-nonane-1,6-dione, with the Pd-catalyzed coupling of the enol triflates with CO and amino alcohols as the key steps for the construction of the oxazoline moiety. The structure of the ligand (R,S,S)-1b was … chicken tikka masala james martinWebSpinPhox/Ir-I catalysts have been demonstrated to be highly enantioselective in the asymmetric hydrogenation of the CC bonds in the exocyclic,-unsaturated cyclic carbonyls, … hunter x hunter animem