Phospho tbk1 cst
WebCytosolic double-stranded DNA detection also feeds into the TBK1-IRF-3 signaling axis through multiple portals. The major cytosolic DNA binding sensor is cyclic GMP-AMP synthase (cGAS) which responds to DNA binding by producing the cyclic dinucleotide c-GMP-AMP (cGAMP). cGAMP binds to STING and activates TBK1-IRF-3-mediated IFN … WebFigure Legend Snippet: TAOK1 promotes TBK1-IRF3 complex formation. a HEK293T cells were transfected with plasmids encoding HA-TBK1, Flag-IRF3, and varying doses of a plasmid encoding Myc-TAOK1 (0.5, 1.0, and 1.5 μg). Cells were harvested 24 h after transfection for immunoblot analysis as indicated with the antibody to Flag tag. b …
Phospho tbk1 cst
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WebDec 9, 2013 · IPS-1 and STING localize to the mitochondria and endoplasmic reticulum, respectively, whereas it is unclear where phosphorylated TBK1 is localized in response to … WebWhile TBK1 is known to phosphorylate cargo receptors to promote ubiquitin binding, it is unknown whether TBK1 phosphorylates other proteins to promote mitophagy. Using global quantitative proteomics, we identified S72 in RAB7A, a RAB previously linked with mitophagy, as a dynamic target of TBK1 upon mitochondrial depolarization.
Web丁香通为您找到78条tbk1抗体信息，包括tbk1抗体报价行情，优质供应商，图片，品牌等最新信息，丁香通为买家提供用户服务，诚信保障等服务，批发采购tbk1抗体,上丁香通。 ... Phospho-TBK1 (Ser172) Rabbit ... 品牌：Abcam\santa\cst ... WebNov 9, 2024 · TBK1 phosphorylation was upregulated in the trophoblasts and placenta in response to LPS. Pharmacological and genetic inhibition of TBK1 in trophoblasts ameliorated LPS-induced NLRP3 inflammasome activation, placental inflammation, and subsequent interleukin (IL)-1 production.
WebTBK1 (TANK-binding kinase 1)/NAK (NF-κB activating kinase) is an IκB kinase (IKK)-activating kinase and can activate IKK through direct phosphorylation (1). TBK1 was identified through association with the TRAF binding protein, TANK, and found to function upstream of NIK and IKK in the activation of NF-κB (2). WebTBK1 (TANK-binding kinase 1)/NAK (NF-κB activating kinase) is an IκB kinase (IKK)-activating kinase and can activate IKK through direct …
WebChromatin immunoprecipitations were performed with cross-linked chromatin from HaCaT cells Hep G2 cells starved overnight and treated with IL-6 (100 ng/ml) for 30 minutes and either Phospho-Stat3 (Tyr705) (D3A7) XP ® Rabbit mAb or Normal Rabbit IgG #2729 using SimpleChIP ® Plus Sonication Chromatin IP Kit #56383.
http://www.asbio.com.cn/shop/category/102-392/page/5 shoprite greater morristown pharmacyWebConfocal immunofluorescent analysis of THP-1 cells, untransfected (left) or transfected with Poly (I:C) (2.5 μg/ml, 6 hr; right), using Phospho-IRF-3 (Ser386) (E7J8G) XP ® Rabbit mAb (green) and β-Actin (13E5) Rabbit mAb (Alexa Fluor ® 647 Conjugate) #8584 (red). Blue = Hoechst 33342 #4082 (fluorescent DNA dye). Show More shoprite greenacresWebAMPK plays a predominant role as the master regulator of cellular energy homeostasis, controlling downstream effectors that regulate cell growth and apoptosis in response to … shoprite groceries instacartWebWestern blot analysis of extracts from THP-1 cells differentiated with TPA #4174 (80 nM, overnight) followed by treatment with LPS (1 μg/ml), up to 24h, using Phospho-TBK1/NAK (Ser172) (D52C2) XP ® Rabbit mAb (upper), or total TBK1/NAK (D1B4) Rabbit mAb #3504 (lower). Show More shoprite grade a stamford ctWebPhospho-eIF4E (Ser209) Antibody detects endogenous levels of eIF4E only when phosphorylated at serine 209. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E. shoprite greenacres port elizabethWebPhospho-TBK1/NAK (Ser172) (D52C2) XP ® Rabbit mAb (Alexa Fluor ® 488 Conjugate) 商城价格 登录后可查看价格 shoprite greenwich nj digital couponsWebPhospho-AMPKα (Thr172) (40H9) Rabbit mAb detects endogenous AMPKα1 only when phosphorylated at threonine 183 and endogenous AMPKα2 only when phosphorylated at threonine 172. The antibody does … shoprite greenfield family