Cytoplasmic retention signal
WebAug 1, 1994 · Although the cytoplasmic retention signal region is outside the cyclin box, its sequence is well conserved in human cyclin B2, and is both necessary and sufficient … WebApr 8, 2014 · When present within 4-residues of the TMD it serves as a Golgi export signal, but when located at the C-terminus of the 68-residue p14 cytoplasmic endodomain it functions as an ER retention signal. The PBM has no effect on protein trafficking when located at an internal position in the cytoplasmic domain.
Cytoplasmic retention signal
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WebApr 8, 2014 · Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signaling. The hominoid … WebOct 13, 1995 · The ER retention signal of the cytoplasmic domain could not be localized to a single amino acid segment by deletion analysis. These results show that cytochrome P450 2C2 contains redundant, complex ER retention signals in its cytoplasmic and N-terminal hydrophobic domains and that the function of the N-terminal signal is context …
WebSignal-Based Retention of Golgi Resident Proteins via Carboxy-Terminal Lysine-Based Motifs The glycosylation of proteins and lipids depends on nucleotide-sugar conjugates that are translocated from the cytoplasm into the lumen of the ER or Golgi via multispanning membrane proteins called nucleotide-sugar transporters (NSTs) ( Berninsone and ... WebJul 15, 2004 · In fact, the nucleolar retention signal of human T cell leukemia virus type I protein p27 x-III and the HIV-Tat protein are also highly positively charged (Siomi et al., …
WebMar 1, 2013 · A cytoplasm retention signal would, in theory, not be affected by these interventions, whereas we observed nuclear accumulation of Htt in the setting of inhibition of nuclear export. Given its high degree of evolutionary conservation, beyond the four amino acid NES motif, it is highly plausible that N17 contains overlapping, but distinct ... WebAug 1, 1997 · The JNK signal transduction pathway is activated in response to environmental stress and by the engagement of several classes of cell surface receptors, including cytokine receptors, serpentine receptors, and receptor tyrosine kinases ( 1 ). Genetic studies of Drosophila have demonstrated that JNK is required for early …
WebJan 12, 2024 · The cytoplasmic tail is still not well known but contains an ER retrieval signal that is shared by other similar viruses. ... of the cell by as yet unknown retention …
WebThis new understanding of the determinants of nuclear retention and cytoplasmic export provides a deeper understanding of how information flow is regulated in eukaryotic cells. Ultimately these processes promote … dewa m stationWebThe ER retention signal of the cytoplasmic domain could not be localized to a single amino acid segment by deletion analysis. These results show that cytochrome P450 2C2 … church of jesus christ of latter dsWebIntegrins and Signal Transduction. As discussed in Chapters 11 and 12, the integrins are the major receptors responsible for the attachment of cells to the extracellular matrix.At … church of jesus christ of latter intsWebCytokine release syndrome (CRS) is a form of systemic inflammatory response syndrome (SIRS) that can be triggered by a variety of factors such as infections and certain drugs. … church of jesus christ of latter day stsWebCytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21(Cip1/Waf1) in phorbol 12 … dewa multiplication factorWebAug 1, 1999 · studies provide evidence for a cytoplasmic targeting/retention signal (CTRS) in MA that is responsible for intracytoplasmic capsid assembly in Type D retroviruses. church of jesus christ of latter day ssER retention refers to proteins that are retained in the endoplasmic reticulum, or ER, after folding; these are known as ER resident proteins. Protein localization to the ER often depends on certain sequences of amino acids located at the N terminus or C terminus. These sequences are known as signal peptides, molecular signatures, or sorting signals. dewa mushrif control room